Structure of PDB 6yuf Chain C Binding Site BS01

Receptor Information
>6yuf Chain C (length=456) Species: 284812 (Schizosaccharomyces pombe 972h-) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YITKIVIQGFKSYKDYTVIEPLSPHHNVIVGRNGSGKSNFFAAIRFVLSD
AYTHLSREERQALLHEGPGATVMSAYVEVTFANADNRFPTGKSEVVLRRT
IGLKKDEYSLDKKTVSKTEVINLLESAGFSRSNPYYIVPQGRVTSLTNAK
DSERLELLKEVAGTQIYENRRAESNKIMDETIQKSEKIDELLQYIEERLR
ELEEEKNDLAVYHKKDNERRCLEYAIYSREHDEINSVLDSSNAIVKKLHK
INEALKDYGSVNKKAYEQFNNFTKQRDSLLARREELRRSQESISELTTVL
DQRKDEAIERTFKQVAKSFSEIFVKLVPAGRGELVMNRRSISIRVSFNSK
DDEQLNINQLSGGQKSLCALTLIFAIQRCDPAPFNILDECDANLDAQYRS
AIAAMVKEMSKTSQFICTTFRPEMVKVADNFYGVMFNHKVSTVESISKEE
AMAFVE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6yuf A Structure-Based Mechanism for DNA Entry into the Cohesin Ring.
Resolution3.94 Å
Binding residue
(original residue number in PDB)		L56 K118
Binding residue
(residue number reindexed from 1)		L55 K117
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003690 double-stranded DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
GO:0061776 topological DNA co-entrapment activity
Biological Process
GO:0007064 mitotic sister chromatid cohesion
GO:0031619 homologous chromosome orientation in meiotic metaphase I
GO:0051276 chromosome organization
GO:0051301 cell division
GO:0140588 chromatin looping
Cellular Component
GO:0000779 condensed chromosome, centromeric region
GO:0005634 nucleus
GO:0005694 chromosome
GO:0005829 cytosol
GO:0008278 cohesin complex
GO:0030892 mitotic cohesin complex
GO:0030893 meiotic cohesin complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6yuf, PDBe:6yuf, PDBj:6yuf
PDBsum6yuf
PubMed32755595
UniProtO42649|SMC3_SCHPO Structural maintenance of chromosomes protein 3 (Gene Name=psm3)

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