Structure of PDB 6yn1 Chain C Binding Site BS01

Receptor Information
>6yn1 Chain C (length=94) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAV
MALQEASEAYLVALFEDTNLCAIHAKRVTIMPKDIQLARRIRGE
Ligand information
>6yn1 Chain E (length=22) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
PNEYDLNDSFLDDEEEDSDWEP
Receptor-Ligand Complex Structure
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PDB6yn1 Crystal structure of histone chaperone APLF acidic domain bound to the histone H2A-H2B-H3-H4 octamer
Resolution2.35 Å
Binding residue
(original residue number in PDB)		R63 K64 L65 Q68 R72 A75 L82 R83 F84 Q85 S86 M90 Q93
Binding residue
(residue number reindexed from 1)		R24 K25 L26 Q29 R33 A36 L43 R44 F45 Q46 S47 M51 Q54
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6yn1, PDBe:6yn1, PDBj:6yn1
PDBsum6yn1
PubMed35895815
UniProtP02302|H3C_XENLA Histone H3.3C (Gene Name=h3-5)

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