Structure of PDB 6y5e Chain C Binding Site BS01

Receptor Information
>6y5e Chain C (length=107) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTA
EILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPN
IQAVLLP
Ligand information
>6y5e Chain I (length=153) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
atcctggagaatcccggtgccgaggccgctcaattggtcgtagacagctc
tagcaccgcttaaacgcacgtacgcgctgtcccccgcgttttaaccgcca
aggggattactccctagtctccaggcacgtgtcagatatatacatcctgt
gat
Receptor-Ligand Complex Structure
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PDB6y5e Structural mechanism of cGAS inhibition by the nucleosome.
Resolution3.15 Å
Binding residue
(original residue number in PDB)		R12 A13 K16 R18 R33 R78
Binding residue
(residue number reindexed from 1)		R1 A2 K5 R7 R22 R67
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6y5e, PDBe:6y5e, PDBj:6y5e
PDBsum6y5e
PubMed32911482
UniProtQ16777|H2A2C_HUMAN Histone H2A type 2-C (Gene Name=H2AC20)

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