Structure of PDB 6y45 Chain C Binding Site BS01

Receptor Information
>6y45 Chain C (length=163) Species: 953739 (Streptomyces venezuelae ATCC 10712) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKLSGGVEWALHCCVVLTAASRPVPAARLAELADVSPSYLAKQMQALSRA
GLVRSVQGKTGGYVLTRPAVEITLLDVVQAVDGPDPAFVCTEIRQRGPLA
TPPEKCTKACPIARAMGAAEAAWRASLAATTIADLVATVDDESGPDALPG
VGAWLIEGLGHHH
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain6y45 Chain A Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6y45 Electron and Proton Transfers Modulate DNA Binding by the Transcription Regulator RsrR.
Resolution1.68 Å
Binding residue
(original residue number in PDB)		F88 C90 E92 R94 C110 I112 A113
Binding residue
(residue number reindexed from 1)		F88 C90 E92 R94 C110 I112 A113
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6y45, PDBe:6y45, PDBj:6y45
PDBsum6y45
PubMed32078310
UniProtF2RGC9

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