Structure of PDB 6xwh Chain C Binding Site BS01

Receptor Information
>6xwh Chain C (length=80) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
KRQRNRCQYCRYQKCLAMGMKREAVQEERQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6xwh Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		K145 H146 Y147 K160 R164 V205 Q206 E208 R209
Binding residue
(residue number reindexed from 1)		K15 H16 Y17 K30 R34 V75 Q76 E78 R79
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6xwh, PDBe:6xwh, PDBj:6xwh
PDBsum6xwh
PubMed32974652
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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