Structure of PDB 6xwg Chain C Binding Site BS01

Receptor Information
>6xwg Chain C (length=79) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDK
RQRNRCQYCRYQKCLAMGMKREAVQEERQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6xwg Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR-RXR.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		K145 H146 Y147 K160 R164 R172 Q206 E208 R209
Binding residue
(residue number reindexed from 1)		K14 H15 Y16 K29 R33 R41 Q75 E77 R78
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6xwg, PDBe:6xwg, PDBj:6xwg
PDBsum6xwg
PubMed32974652
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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