Structure of PDB 6xny Chain C Binding Site BS01

Receptor Information
>6xny Chain C (length=548) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAITGRQIFQPLHALRNAEKV
LLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGLASSVDEYPVDTIAKRFRY
DSALVSALMDMEEDILEGMRSQDLDDYLNGPFTVVVKESCDGMGDVSEKH
GSGPAVPEKAVRFSFTVMRITIEHGSQNVKVFEEPKPNSVLCCKPLCLML
ADESDHETLTAILSPLIAEREAMKSSELTLEMGGIPRTFKFIFRGTGYDE
KLVREVEGLEASGSVYICTLCDTTRLEASQNLVFHSITRSHAENLQRYEV
WRSNPYHESVEELRDRVKGVSAKPFIETVPSIDALHCDIGNAAEFYKIFQ
LEIGEVYKHPNASKEERKRWQATLDKHLRKRMNLKPIMMMNGNFARKLMT
QETVDAVCELIPSEERHEALRELMDLYLKMKPVWRSSCPAKECPESLCQY
SFNSQRFAELLSTKFKYRYEGKITNYFHKTLAHVPEIIERDGSIGAWASE
GNESGNKLFRRFRKMNARQSKCYEMEDVLKHHWLYTSKYLQKFMNAHN
Ligand information
Receptor-Ligand Complex Structure
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PDB6xny Structural basis for the activation and suppression of transposition during evolution of the RAG recombinase.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		M602 G603 K618 L794 H795 M847 M848 M849 N850 G851 N852 R855 K856 E959 E962 S963 K966 R969
Binding residue
(residue number reindexed from 1)		M143 G144 K159 L335 H336 M388 M389 M390 N391 G392 N393 R396 K397 E500 E503 S504 K507 R510
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6xny, PDBe:6xny, PDBj:6xny
PDBsum6xny
PubMed32945578
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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