Structure of PDB 6x0n Chain C Binding Site BS01

Receptor Information
>6x0n Chain C (length=110) Species: 8355 (Xenopus laevis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRAKAKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLP
NIQSVLLPKK
Ligand information
>6x0n Chain I (length=157) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
caatacatgcacaggatgtatatatctgacacgtgcctggagactaggga
gtaatccccttggcggttaaaacgcgggggacagcgcgtacgtgcgttta
agcggtgctagagctgtctacgaccaattgagcggcctcggcaccgggat
tctccag
Receptor-Ligand Complex Structure
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PDB6x0n Bridging of DNA breaks activates PARP2-HPF1 to modify chromatin.
Resolution10.0 Å
Binding residue
(original residue number in PDB)		R11 A12 K13 A14 K15 T16 R17 R20 G28 R29 R32 R77
Binding residue
(residue number reindexed from 1)		R2 A3 K4 A5 K6 T7 R8 R11 G19 R20 R23 R68
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function
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Cellular Component
External links
PDB RCSB:6x0n, PDBe:6x0n, PDBj:6x0n
PDBsum6x0n
PubMed32939087
UniProtP06897|H2A1_XENLA Histone H2A type 1

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