Structure of PDB 6wvw Chain C Binding Site BS01

Receptor Information
>6wvw Chain C (length=73) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEEMQRRADQLADESLESTRRMLQLVEESKDAGIRTLVMLDEQGEQLDPV
EEGMNHINQDMKEAEKNLKDLGK
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain6wvw Chain C Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6wvw Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies.
Resolution2.11 Å
Binding residue
(original residue number in PDB)		G54 D58
Binding residue
(residue number reindexed from 1)		G44 D48
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000149 SNARE binding
GO:0005249 voltage-gated potassium channel activity
GO:0017075 syntaxin-1 binding

View graph for
Molecular Function
External links
PDB RCSB:6wvw, PDBe:6wvw, PDBj:6wvw
PDBsum6wvw
PubMed33147442
UniProtP60881|SNP25_RAT Synaptosomal-associated protein 25 (Gene Name=Snap25)

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