Structure of PDB 6we9 Chain C Binding Site BS01
Receptor Information
>6we9 Chain C (length=164) Species:
9606
(Homo sapiens) [
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GTSKLKYVLQDARFFLIKSNNHENVSLAKAKGVWSTLPVNEKKLNLAFRS
ARSVILIFSVRESGKFQGFARLSSESHHGGSPIHWVLPAGMSAKMLGGVF
KIDWICRRELPFTKSAHLTNPWNEHKPVKIGRDGQEIELECGTQLCLLFP
PDESIDLYQVIHKM
Ligand information
>6we9 Chain F (length=9) [
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cgcggactc
Receptor-Ligand Complex Structure
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PDB
6we9
Biochemical and structural basis for YTH domain of human YTHDC1 binding to methylated adenine in DNA.
Resolution
1.59 Å
Binding residue
(original residue number in PDB)
K361 N363 W377 S378 T379 E405 A432 G433 M438 K472 I473 G474 R475 D476
Binding residue
(residue number reindexed from 1)
K18 N20 W34 S35 T36 E62 A89 G90 M95 K129 I130 G131 R132 D133
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
View graph for
Molecular Function
External links
PDB
RCSB:6we9
,
PDBe:6we9
,
PDBj:6we9
PDBsum
6we9
PubMed
32663306
UniProt
Q96MU7
|YTDC1_HUMAN YTH domain-containing protein 1 (Gene Name=YTHDC1)
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