Structure of PDB 6w6h Chain C Binding Site BS01

Receptor Information
>6w6h Chain C (length=636) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QALQKYSTDLTARAREGKLDPVIGRDNEIRRVVQVLSRRTKNNPVLIGEP
GVGKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEER
LKAVLDDIKNSAGQIITFIDELHTIVGAGATGAMDAGNMIKPMLARGELR
LVGATTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEV
HHGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAASRLRMEIDSRP
VEIDEVERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELT
TRWQNEKNAIEIVRDLKEMLKEEVGPDDIADVVSAWTGIPAGRLLEGETA
KLLRMEDELGKRVIGQKAAVTAVSDAVRRSRAGVSDPNRPTGAFMFLGPT
GVGKTELAKALADFLFDDERAMVRIDMSEYGEKHTVARLIGAPPGYVGYE
AGGQLTEAVRRRPYTVVLFDEIEKAHPDVFDVLLQVLDEGRLTDGHGRTV
DFRNTILILTSNLGSGGSAEQVLAAVRATFKPEFINRLDDVLIFEGLNPE
ELVRIVDIQLAQLGKRLAQRRLQLQVSLPAKRWLAQRGFDPVYGARPLRR
LVQQAIGDQLAKMLLAGQVHDGDTVPVNVSPDADSL
Ligand information
>6w6h Chain N (length=26) Species: 1773 (Mycobacterium tuberculosis) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
AAAAAAAAAAAAAAAAAAAAAAAAAA
Receptor-Ligand Complex Structure
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PDB6w6h Structural basis for aggregate dissolution and refolding by the Mycobacterium tuberculosis ClpB-DnaK bi-chaperone system.
Resolution3.3 Å
Binding residue
(original residue number in PDB)		K250 Y251 T289 G654 Y655 V656
Binding residue
(residue number reindexed from 1)		K92 Y93 T131 G445 Y446 V447
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016887 ATP hydrolysis activity
Biological Process
GO:0009408 response to heat
GO:0034605 cellular response to heat
GO:0042026 protein refolding
Cellular Component
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0009274 peptidoglycan-based cell wall

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6w6h, PDBe:6w6h, PDBj:6w6h
PDBsum6w6h
PubMed34038719
UniProtP9WPD1|CLPB_MYCTU Chaperone protein ClpB (Gene Name=clpB)

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