Structure of PDB 6vqw Chain C Binding Site BS01

Receptor Information
>6vqw Chain C (length=297) Species: 287 (Pseudomonas aeruginosa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTDPEALLLLPRLSIQNANAISSPLTWGFPSPGAFTGFVHALQRRVGISL
DIELDGVGIVCHRFEAQISQPAGKRTKVFNLTRNPLNRDGSTAAIVEEGR
AHLEVSLLLGVHGDGLDDHPAQEIARQVQEQAGAMRLAGGSILPWCNERF
PAPNAELLMLGGSDEQRRKNQRRLTRRLLPGFALVSREALLQQHLETLRT
TLPEATTLDALLDLQVRDKPGWLVPIPAGYNALSPLYLPGEVRNARDRET
PLRFVENLFGLGEWLSPHRVAALSDLLWYHHAEPDKGLYRWSTPRFV
Ligand information
>6vqw Chain K (length=40) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cuaagaaauucacggcgggcuugauguccgcgucuaccug
........................................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6vqw Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM.
Resolution3.42 Å
Binding residue
(original residue number in PDB)
N21 P26 A36 F40 R46 R85 N86 R138 L139 G141 R271 N282
Binding residue
(residue number reindexed from 1)
N19 P24 A34 F38 R44 R83 N84 R136 L137 G139 R246 N257
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
Biological Process
GO:0051607 defense response to virus

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:6vqw, PDBe:6vqw, PDBj:6vqw
PDBsum6vqw
PubMed32170016
UniProtQ02MM0|CSY2_PSEAB CRISPR-associated protein Csy2 (Gene Name=csy2)

[Back to BioLiP]