Structure of PDB 6u0y Chain C Binding Site BS01

Receptor Information
>6u0y Chain C (length=264) Species: 522373 (Stenotrophomonas maltophilia K279a) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
APLPQLRAYTVDASWLQPMAPLQVADHTWQIGTEDLTALLVQTAEGAVLL
DGGMPQMAGHLLDNMKLRGVAPQDLRLILLSHAHADHAGPVAELKRRTGA
HVAANAETAVLLARGGSNDLHFGDGITYPPASADRIIMDGEVVTVGGIAF
TAHFMPGHTPGSTAWTWTDTRDGKPVRIAYADSLSAPGYQLKGNPRYPRL
IEDYKRSFATVRALPCDLLLTPHPGASNWNYAVGSKASAEALTCNAYADA
AEKKFDAQLARETA
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain6u0y Chain C Residue 301 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6u0y Crystal Structure of the metallo-beta-lactamase L1 from Stenotrophomonas maltophilia
Resolution1.7 Å
Binding residue
(original residue number in PDB)		H105 H107 H181
Binding residue
(residue number reindexed from 1)		H82 H84 H158
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H105 H107 D109 H110 H181 Y212 H246
Catalytic site (residue number reindexed from 1) H82 H84 D86 H87 H158 Y189 H223
Enzyme Commision number 3.5.2.6: beta-lactamase.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding
GO:0008800 beta-lactamase activity
Biological Process
GO:0017001 antibiotic catabolic process

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Molecular Function
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Biological Process
External links
PDB RCSB:6u0y, PDBe:6u0y, PDBj:6u0y
PDBsum6u0y
PubMed
UniProtB2FTM1

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