Structure of PDB 6tw1 Chain C Binding Site BS01

Receptor Information
>6tw1 Chain C (length=740) Species: 1129347 (Influenza A virus (A/little yellow-shouldered bat/Guatemala/060/2010(H17N10))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGMERIKELMEMVKNSRMREILTTTSVDHMAVIKKYTSGRQEKNPALRMK
WMMAMKYPISASSRIREMIPEKDEDGNTLWTNTKDAGSNRVLVSPNAVTW
WNRAGPVSDVVHYPRVYKMYFDRLERLTHGTFGPVKFYNQVKVRKRVDIN
PGHKDLTSREAQEVIMEVVFPNEVGARTLSSDAQLTITKEKKEELKNCKI
SPIMVAYMLERELVRRTRFLPIAGATSSTYVEVLHLTQGTCWEQQYTPGG
EAENDDLDQTLIIASRNIVRRSIVAIDPLASLLSMCHTTSISSEPLVEIL
RSNPTDEQAVNICKAALGIRINNSFSFGGYNFKRVKGSSQRTEKAVLTGN
LQTLTMTIFEGYEEFNVSGKRASAVLKKGAQRLIQAIIGGRTLEDILNLM
ITLMVFSQEEKMLKAVRGDLNFVNRANQRLNPMYQLLRHFQKDSSTLLKN
WGTEEIDPIMGIAGIMPDGTINKTQTLMGVRLSQGGVDEYSFNERIRVNI
DKYLRVRNEKGELLISPEEVSEAQGQEKLPINYNSSLMWEVNGPESILTN
TYHWIIKNWELLKTQWMTDPTVLYNRIEFEPFQTLIPKGNRAIYSGFTRT
LFQQMRDVEGTFDSIQIIKLLPFSAHPPSLGRTQFSSFTLNIRGAPLRLL
IRGNSQVFNYNQMENVIIVLGKSVGSPERSILTESSSIESAVLRGFLILG
KANSKYGPVLTIGELDKLGRGEKANVLIGQGDTVLVMKRK
Ligand information
>6tw1 Chain V (length=33) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aguaguaacaagagcaauguguccgucucugcu
.<<....>>........................
Receptor-Ligand Complex Structure
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PDB6tw1 A Structure-Based Model for the Complete Transcription Cycle of Influenza Polymerase.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R38 K41 A52 M53 K54 R216
Binding residue
(residue number reindexed from 1)		R40 K43 A54 M55 K56 R218
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6tw1, PDBe:6tw1, PDBj:6tw1
PDBsum6tw1
PubMed32304664
UniProtH6QM90

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