Structure of PDB 6thh Chain C Binding Site BS01

Receptor Information

>6thh Chain C (length=816) Species: 1241935 (Sulfolobus islandicus LAL14/1)

MRNLKRIVMGENKLIGLVRTALDSITLGQGVNEAKIKSPQSYAFHTISVG
TISLDICKAIYSSSEIGRKQLENLSKKYNMPFEDLWFYGGFLHDWNKLSG
KEENKEELTKKIIDKLKLPNEFLHGISTMAEGHLPDNLHLPLWVSIKLAD
MLLISDIGSVRDVFYFANSDSYRNAIEALKEYNLELNYVSSTFRLFTLIA
SKELLNDVFNEKSGYFPLISYADGIVFLKRKNSQPVLLSKIVDLLSRQVF
SSSSEVIEEKISDIEKCIKNKEELFRQMNIDVKSAIYDEEGKVKQINAFL
PTKVCKPFEDVVGNLDNKSKLQVAREVIERNRKDIPFGLLIYFVNKFSKN
EEDYIRKGLGINEKSLKYLLNIGDVQKALDKILELLEKRYAEQSSDKTLL
YYVKFSSSGNIIDDLPKITDRPNDYCVVCGMPIYSSNPVRFVQVRDDWKV
CPICIYEANLMKDRVKPPYFIVTFYPGVPISLLNIIDFDFSQSSIKYYID
EEKDTYFTAFEKMGGRLEPYVKKVLPAYFSSKVIIKASEVSNFSLSTRLS
KSELNKLLPYAPMISMIFLTSPVLISSNLYEMPIHERVISITSTYNYTFM
KSLNSNLLTLYSIFAYSAKYDAMRKICGRSDLDNCLGYLTEEMDLYSSVD
PALGVLSIGMGVGTPIDTDEKFFSAFLPVSGYLLKVTGKVSKMGETLKSS
IFSIAYALKDIIKSQKVSKYDVTGFLRDGVDMFFKTTSVIKDKEDRIGIS
VNAAISSLENKYALDDQHRAQVYSALQDIFKTLYSIEEESDRSLAISIAN
TLSNWLYIAYKLVLQG

Ligand information

• Ligand ID: ZN
• InChI: InChI=1S/Zn/q+2
• InChIKey: PTFCDOFLOPIGGS-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Zn++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Zn+2]
• Formula: Zn
• Name: ZINC ION
• ChEMBL: CHEMBL1236970
• DrugBank: DB14532
• PDB chain: 6thh Chain C Residue 902

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6thh Structural basis for inhibition of an archaeal CRISPR-Cas type I-D large subunit by an anti-CRISPR protein.
• Resolution: 3.48 Å
• Binding residue (original residue number in PDB): C429 C432
• Binding residue (residue number reindexed from 1): C426 C429
• Annotation score: 4

Gene Ontology

Molecular Function

• GO:0046872 metal ion binding

External links

• PDB: RCSB:6thh, PDBe:6thh, PDBj:6thh
• PDBsum: 6thh
• PubMed: 33239638
• UniProt: M9U4Y8