Structure of PDB 6tga Chain C Binding Site BS01

Receptor Information
>6tga Chain C (length=148) Species: 1061 (Rhodobacter capsulatus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TDTARLRAILAAHRGREGALLPILHDVQAAFGFIPEDAYAPIAADLGLTR
AEVAGVVGFYHDFRKAPAGRHVIKLCRAEACQAMGMDAVQARLESALGLR
LGDSSEAVTLEAVYCLGLCACAPAAMVDDRLVGRLDAAAVAGIVAELG
Ligand information
Ligand IDFES
InChIInChI=1S/2Fe.2S
InChIKeyNIXDOXVAJZFRNF-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04[Fe]1S[Fe]S1
CACTVS 3.341
OpenEye OEToolkits 1.5.0		S1[Fe]S[Fe]1
FormulaFe2 S2
NameFE2/S2 (INORGANIC) CLUSTER
ChEMBL
DrugBank
ZINC
PDB chain6tga Chain C Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6tga Cryo-EM structures reveal intricate Fe-S cluster arrangement and charging in Rhodobacter capsulatus formate dehydrogenase.
Resolution3.26 Å
Binding residue
(original residue number in PDB)		C77 A79 C82 C116 L119 C120
Binding residue
(residue number reindexed from 1)		C76 A78 C81 C115 L118 C119
Annotation score4
Enzymatic activity
Enzyme Commision number 1.2.1.2: Transferred entry: 1.17.1.9.
Gene Ontology
Molecular Function
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0051537 2 iron, 2 sulfur cluster binding

View graph for
Molecular Function
External links
PDB RCSB:6tga, PDBe:6tga, PDBj:6tga
PDBsum6tga
PubMed32313256
UniProtD5AQH2

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