Structure of PDB 6ske Chain C Binding Site BS01

Receptor Information
>6ske Chain C (length=1752) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
CDLSGFVRPDPVIISSPLSTFFSDAPGRNPIVPETQVLHEEIEVPGSSIK
LIYLSSRTAGYKSLLKIIMTQSLVPLNLIKVHLMVAVEGHLFQKSFLASP
NLAYTFIWDKTDAYGQKVYGLSDAVVSVGFEYETCPSLILWEKRTALLQG
FELDPSNLGGWSLDKHHVLNVKSGILHKGNGENQFLTQQPAVITSIMGNG
RRRSISCPSCNGLAEGNKLLAPVALAVGIDGSLFVGDFNYIRRIFPSRNV
TSILELRNKEFKHSNNPAHKYYLAVDPVSGSLYVSDTNSRRIYKVKSLTG
TKDLAGNSEVVAGTGEQCLPFDEARCGDGGKAVDATLMSPRGIAVDKYGL
MYFVDATMIRKVDQNGIISTLLGSNDLTAVRPLSCDSSMDVSQVRLEWPT
DLAVDPMDNSLYVLENNVILRITENHQVSIIAGRPMHCQVPGIDYSLSKL
AIHSALESASAIAISHTGVLYISETDEKKINRLRQVTTNGEICLLAGAAS
DCDCKNDVNCNCYSGDDGYATDAILNSPSSLAVAPDGTIYIADLGNIRIR
AVSKNRPILNSFNQYEAASPGEQELYVFNADGIHQYTLSLVTGEYLYNFT
YSSDNDVTEVMDSNGNSLKVRRDASGMPRHLLMPDNQIVTLAVGTNGGLK
LVSTQTLELGLMTYNGNSGLLATKSDETGWTTFYDYDHEGRLTNVTRPTG
VVTSLHREMEKSITIDIENSNRDDDVTVITNLSSVEASYTVVQDQVRNSY
QLCNNGTLRVMYANGMSISFHSEPHVLAGTVTPTIGRCNISLPMENGLNS
IEWRLRKEQIKGKVTVFGRKLRVHGRNLLSIDYDRNIRTEKIYDDHRKFT
LRIIYDQLGRPFLWLPSSGLAAVNVSYFFNGRLAGLQRGAMSERTDIDKQ
GRIISRMFADGKVWSYTYLEKSMVLLLQSQRQYIFEYDSSDRLHAVTMPS
VARHSMSTHTSVGYIRNIYNPPESNASVIFDYSDDGRILKTSFLGTGRQV
FYKYGKLSKLSEIVYDSTAVTFGYDETTGVLKMVNLQSGGFSCTIRYRKI
GPLVDKQIYRFSEEGMVNARFDYTYHDNSFRIASIKPIISETPLPVDLYR
YDEISGKVEHFGKFGVIYYDINQIITTAVMTLSKHFDTHGRIKEVQYEMF
RSLMYWMTVQYDSMGRVTKRELKLGPYANTTKYTYDYDGDGQLQSVAVND
RPTWRYSYDLNGNLHLLNPGNSVRLMPLRYDLRDRITRLGDIPYKIDDDG
FLCQRGSDVFEYNSKGLLTRAYNKANGWNVQYRYDGLGRRASCKTNLGHH
LQYFYADLHNPTRVTHVYNHSNSEITSLYYDLQGHLFAMESSSGEEYYVA
SDNTGTPLAVFSINGLMIKQLQYTAYGEIYYDSNPDFQLVIGFHGGLYDP
LTKLVHFTQRDYDVLAGRWTSPDYTMWKNIGREPAPFNLYMFKSNNPLSN
ELDLKNYVTDVKSWLVMFGFQLSNIIPGFPRAKMYFVSPPYELTESQACE
NGQLITGVQQTTERHNQAFMALEGQVISKRLHASIREKAGHWFATSTPII
GKGIMFAVKKGRVTTGISSIATDDSRKIASVLNSAHYLEKMHYSIEGKDT
HYFVKIGSADSDLVTLAMTSGRKVLDSGVNVTVSQPTLLINGRTRRFTNI
EFQYSTLLINIRYGLTADTLDEEKARVLDQARQRALGSAWAKEQQKARDG
REGSRVWTDGEKQQLLNTGRVQGYEGYYVLPVEQYPELADSSSNIQFLRQ
NE
Ligand information
Ligand IDMAN
InChIInChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6+/m1/s1
InChIKeyWQZGKKKJIJFFOK-PQMKYFCFSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(C1C(C(C(C(O1)O)O)O)O)O
CACTVS 3.341OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O
OpenEye OEToolkits 1.5.0C([C@@H]1[C@H]([C@@H]([C@@H]([C@H](O1)O)O)O)O)O
ACDLabs 10.04OC1C(O)C(OC(O)C1O)CO
FormulaC6 H12 O6
Namealpha-D-mannopyranose;
alpha-D-mannose;
D-mannose;
mannose
ChEMBLCHEMBL365590
DrugBank
ZINCZINC000003860903
PDB chain6ske Chain K Residue 5 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ske Structural Basis of Teneurin-Latrophilin Interaction in Repulsive Guidance of Migrating Neurons.
Resolution3.62 Å
Binding residue
(original residue number in PDB)		S2429 N2430
Binding residue
(residue number reindexed from 1)		S1383 N1384
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6ske, PDBe:6ske, PDBj:6ske
PDBsum6ske
PubMed31928845
UniProtQ9DER5|TEN2_CHICK Teneurin-2 (Gene Name=TENM2)

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