Structure of PDB 6qic Chain C Binding Site BS01

Receptor Information
>6qic Chain C (length=627) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SIKEQRESLPVFQFRDQIIQAVKDNQILIVVGETGSGKTTQVTQYLAEAG
FTKYGMIGCTQPRRVAAVSVAKRVAEEVGCQLGQEVGYTIRFEDVTSPAT
KIKYMTDGMLQREILMDPDLKRYSVIMLDEAHERTIATDVLFALLKKTVK
RRPDLKVIVTSATLDAEKFSEYFNSCPIFTIPGRTFPVEILYSREPEPDY
LEAALTTVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKALGPSVPE
LIILPIYSALPSEMQSRIFEPAPPGSRKVVIATNIAETAITIDYIYYVVD
PGFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTGPGKCFRLYTEA
AYQSEMLPTTIPDIQRQNLANTILLLKAMGINDLLRFDFMDPPPVNTMLT
ALEELYALGALDDEGLLTRLGRKMADFPMEPSLSKVLIASVDKGCSDEMV
TIVSMLNLQQIFYRPKDKQQQADQKKAKFHDPTGDHLTLLNVYNAWKNSG
YSNAWCFENYIQARAMRRARDVRQQIVKIMERHRHPIISCGRDTDKIRQA
LCAGFFRNTARKDPGYKTLTEGTPVYLHPSSALFGKQAEWVLYHELVLTT
KEYMHFTTAIEPKWLVEAAPTFFKLAP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6qic Structural basis for RNA translocation by DEAH-box ATPases.
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R611 R612 R639 T654 G656 M657 R660 G774 Q775 E776 S806 T831 N832 K853 L866 D974 P976 R1012 Q1073 I1077 R1080 H1128 P1129 F1134 T1149 K1151 Y1153 H1155
Binding residue
(residue number reindexed from 1)		R63 R64 R91 T106 G108 M109 R112 G226 Q227 E228 S258 T283 N284 K305 L318 D426 P428 R464 Q525 I529 R532 H578 P579 F584 T599 K601 Y603 H605
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6qic, PDBe:6qic, PDBj:6qic
PDBsum6qic
PubMed30828714
UniProtG0S700

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