Structure of PDB 6pzv Chain C Binding Site BS01
Receptor Information
>6pzv Chain C (length=226) Species:
9913
(Bos taurus) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
SPKCTECLQYLDDPELRYEQHPPDAVEEIQILTNERLSIFSYEDLPQHKL
TCFSVYCKRGHLCPIDTGLIEKDVELLFSGSAKPIYEDDPSPEGGINGKN
FGPINEWWIAGFDGGEKALLGFSTSFAEYILMDPSPEYAPLFSVMQEKIY
ISKIVVEFLQSNPDSTYEDLINKIETTVPPCMLNLNRFTEDSLLRHAQFV
VEQVESYDRAGFLSPCMRDLIKLAGV
Ligand information
>6pzv Chain D (length=18) Species:
9606
(Homo sapiens) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
RTKQTARKSTGGKAPRCQ
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6pzv
Direct readout of heterochromatic H3K9me3 regulates DNMT1-mediated maintenance DNA methylation.
Resolution
3.01 Å
Binding residue
(original residue number in PDB)
I425 E426 D428 N460 E461 W462 W463 I464 E483 Q558 S561 Y562 A565
Binding residue
(residue number reindexed from 1)
I70 E71 D73 N105 E106 W107 W108 I109 E128 Q203 S206 Y207 A210
Enzymatic activity
Enzyme Commision number
2.1.1.37
: DNA (cytosine-5-)-methyltransferase.
External links
PDB
RCSB:6pzv
,
PDBe:6pzv
,
PDBj:6pzv
PDBsum
6pzv
PubMed
32675241
UniProt
Q24K09
|DNMT1_BOVIN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)
[
Back to BioLiP
]
