Structure of PDB 6puw Chain C Binding Site BS01

Receptor Information
>6puw Chain C (length=65) Species: 11698,273057 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ELQKQITKIQNFRVYYRDSRDPVWKGPAKLLWKGEGAVVIQDNSDIKVVP
RRKAKIIRDYGKQMA
Ligand information
Receptor-Ligand Complex Structure
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PDB6puw Structural basis for strand-transfer inhibitor binding to HIV intasomes.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		R228 R263
Binding residue
(residue number reindexed from 1)		R17 R52
Enzymatic activity
Enzyme Commision number ?
2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004521 RNA endonuclease activity
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration
Cellular Component
GO:0005737 cytoplasm

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Cellular Component
External links
PDB RCSB:6puw, PDBe:6puw, PDBj:6puw
PDBsum6puw
PubMed32001521
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol);
P39476|DN7D_SACS2 DNA-binding protein 7d (Gene Name=sso7d)

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