Structure of PDB 6pun Chain C Binding Site BS01
Receptor Information
>6pun Chain C (length=388) Species:
6239
(Caenorhabditis elegans) [
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VLPTWSLDSNGEMRSRLSLSEVLDSGDLMKFAVDKTGCQFLEKAVKGSLT
SYQKFQLFEQVIGRKDDFLKLSTNIFGNYLVQSVIGISLATNDDGYTKRQ
EKLKNFISSQMTDMCLDKFACRVIQSSLQNMDLSLACKLVQALPRDARLI
AICVDQNANHVIQKVVAVIPLKNWEFIVDFVATPEHLRQICSDKYGCRVV
QTIIEKLTALTSAAQNLRERALQRLMTSVTNRCQELATNEYANYIIQHIV
SNDDLAVYRECIIEKCLMRNLLSLSQEKFASHVVEKAFLHAPLELLAEMM
DEIFDGYIPHPDTGKDALDIMMFHQFGNYVVQCMLTICCDAVSGRRQTKE
GAISFQDWLKKLHSRVTKERHRLSRFSSGKKMIETLAN
Ligand information
>6pun Chain D (length=7) [
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ugugaau
.......
Receptor-Ligand Complex Structure
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PDB
6pun
A crystal structure of a collaborative RNA regulatory complex reveals mechanisms to refine target specificity.
Resolution
2.099 Å
Binding residue
(original residue number in PDB)
N244 Y245 F285 R288 Q291 Q322 N323 H326 Q329 K360 Y361 C363 R364 Q367 N415 Y416 Q419 K450 S453 H454 E457 F498 N500 Y501 Q504 S553 S554 K557
Binding residue
(residue number reindexed from 1)
N78 Y79 F119 R122 Q125 Q156 N157 H160 Q163 K194 Y195 C197 R198 Q201 N243 Y244 Q247 K278 S281 H282 E285 F326 N328 Y329 Q332 S377 S378 K381
Binding affinity
PDBbind-CN
: Kd=111.7nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
View graph for
Molecular Function
External links
PDB
RCSB:6pun
,
PDBe:6pun
,
PDBj:6pun
PDBsum
6pun
PubMed
31397673
UniProt
Q09312
|FBF2_CAEEL Fem-3 mRNA-binding factor 2 (Gene Name=fbf-2)
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