Structure of PDB 6ppo Chain C Binding Site BS01

Receptor Information
>6ppo Chain C (length=253) Species: 463676 (Rhinovirus C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LKQITIGNSTITTQDSLHTVLAYGEWPTYLSDIDATSVDKPTHPETSADR
FYTLDSVEWQVGSHGWWWKLPDALKDMGVFGQNMYYHSMGRSGFIIHTQC
NATKFHSGALIVAVIPEHQLAYVGGVKVNVGYDHTHPGQSGHQIRGPSQS
NDRSGGKPDEDPLFNCNGTLLGNITIFPHQIINLRTNNSSTIVVPYINCV
PMDNMLKHNNLSLVIIPLVPLRPGSSGINSVPITVTIAPYKSEFSGAMEA
QRQ
Ligand information
>6ppo Chain D (length=25) Species: 463676 (Rhinovirus C) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NINYYKDSASSGLSRDPSKFTQPLV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6ppo Cryo-EM structure of rhinovirus C15a bound to its cadherin-related protein 3 receptor.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		T31 V32 L33 Y35
Binding residue
(residue number reindexed from 1)		T19 V20 L21 Y23
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6ppo, PDBe:6ppo, PDBj:6ppo
PDBsum6ppo
PubMed32152109
UniProtE5D8F2|POLG_HRV15 Genome polyprotein

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