Structure of PDB 6oy5 Chain C Binding Site BS01

Receptor Information
>6oy5 Chain C (length=1111) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MEIKRFGRIREVIPLPPLTEIQVESYRRALQADVPPEKRENVGIQAAFRE
TFPIEELVLDFLEYRLGEPPFPQDECREKDLTYQAPLYARLQLIHKDTGL
IKEDEVFLGHIPLMTEDGSFIINGADRVIVSQIHRSPGVYFTPDPARPGR
YIASIIPLPKRGPWIDLEVEPNGVVSMKVNKRKFPLVLLLRVLGYDQETL
ARELGAYGELVQGLMDESVFAMRPEEALIRLFTLLRPGDPPKRDKAVAYV
YGLIADPRRYDLGEAGRYKAEEKLGIRLSGRTLARFEDGEFKDEVFLPTL
RYLFALTAGVPGHEVDDIDHLGNRRIRTVGELMTDQFRVGLARLARGVRE
RMLMGSEDSLTPAKLVNSRPLEAAIREFFSRSQLSQFKDETNPLSSLRHK
RRISALGPGGLTRERAGFDVRDVHRTHYGRICPVETPEGANIGLITSLAA
YARVDELGFIRTPYRRVVGGVVTDEVVYMTATEEDRYTIAQANTPLEGNR
IAAERVVARRKGEPVIVSPEEVEFMDVSPKQVFSVNTNLIPFLEHDDANR
ALMGSNMQTQAVPLIRAQAPVVMTGLEERVVRDSLAALYAEEDGEVAKVD
GNRIVVRYEDGRLVEYPLRRFYRSNQGTALDQRPRVVVGQRVRKGDLLAD
GPASENGFLALGQNVLVAIMPFDGYNFEDAIVISEELLKRDFYTSIHIER
YEIEARDTKLGPERITRDIPHLSEAALRDLDEEGVVRIGAEVKPGDILVG
RTSFKGESEPTPEERLLRSIFGEKARDVKDTSLRVPPGEGGIVVRTVRLR
RGDPGVELKPGVREVVRVYVAQKRKLQVGDKLANRHGNKGVVAKILPVED
MPHLPDGTPVDVILNPLGVPSRMNLGQILETHLGLAGYFLGQRYISPIFD
GAKEPEIKELLAQAFEVYFGKRKGEGFGVDKREVEVLRRAEKLGLVTPGK
TPEEQLKELFLQGKVVLYDGRTGEPIEGPIVVGQMFIMKLYHMVEDKMHA
RSTGPYSLITQQPLGGKAQFGGQRFGEMEVWALEAYGAAHTLQEMLTLKS
DDIEGRNAAYEAIIKGEDVPEPSVPESFRVLVKELQALALDVQTLDEKDN
PVDIFEGLASK
Ligand information
Receptor-Ligand Complex Structure
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PDB6oy5 Structural basis of reiterative transcription from the pyrG and pyrBI promoters by bacterial RNA polymerase.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R134 F394 G1023 K1024 R1031 M1035
Binding residue
(residue number reindexed from 1)		R127 F387 G1016 K1017 R1024 M1028
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
Biological Process
GO:0006351 DNA-templated transcription
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6oy5, PDBe:6oy5, PDBj:6oy5
PDBsum6oy5
PubMed31965171
UniProtQ8RQE9|RPOB_THET8 DNA-directed RNA polymerase subunit beta (Gene Name=rpoB)

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