Structure of PDB 6om2 Chain C Binding Site BS01

Receptor Information
>6om2 Chain C (length=596) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGI
VEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRS
KQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDAD
GQGFCQGGFSIDFTKADRVLLGGPGSFYWQGQLISDQVAEIVSKYDPNVY
SIKYNNQLATRTAQAIFDDSYLGYSVAVGDFNGDGIDDFVSGVPRAARTL
GMVYIYDGKNMSSLYNFTGEQMAAYFGFSVAATDINGDDYADVFIGAPLF
MDRGSDGKLQEVGQVSVSLQRASGDFQTTKLNGFEVFARFGSAIAPLGDL
DQDGFNDIAIAAPYGGEDKKGIVYIFNGRSTGLNAVPSQILEGQWAARSG
CPPSFGYSMKGATDIDKNGYPDLIVGAFGVDRAILYRARPVITVNAGLEV
YPSILNQDNKTCSLPGTALKVSCFNVRFCLKADGKGVLPRKLNFQVELLL
DKLKQKGAIRRALFLYSRSPSHSKNMTISRGGLMQCEELIAYLRDESEFR
DKLTPITIFMEYRLDYRTAADTTGLQPILNQFTPANISRQAHILLT
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6om2 General structural features that regulate integrin affinity revealed by atypical alpha V beta 8.
Resolution2.77 Å
Binding residue
(original residue number in PDB)
Y178 D218
Binding residue
(residue number reindexed from 1)
Y178 D218
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0008305 integrin complex

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Biological Process

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Cellular Component
External links
PDB RCSB:6om2, PDBe:6om2, PDBj:6om2
PDBsum6om2
PubMed31792290
UniProtP06756|ITAV_HUMAN Integrin alpha-V (Gene Name=ITGAV)

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