Structure of PDB 6n7r Chain C Binding Site BS01

Receptor Information
>6n7r Chain C (length=133) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSALYFQNLPSRPANKENYTRLLLKHINPNNKYAINPSLPLPHNKLLLDD
QMGLLEVSISRSSKMTNQAFLTFVTQEEADRFLEKYTTTALKVQGRKVRM
GKARTNSLLGLSIEMQKYNLDIKKVLKARKLKR
Ligand information
>6n7r Chain R (length=558) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auacuuaccuuaagauaucagaggaaaguccuacugaucaaacaugcgcu
uccaauaguagaaggacguuaagcauuuaucauugaacuauaauuguuca
uugaagucauugaugcaaacuccuuggucacacacacauacggcgcggaa
ggcguguuugcugacguuuccauucccuuguuucaaucauugguuaaucc
cuugauuccuuuggggauuuuuggguuaaacugauuuuuggggcccuuug
uuucuucugccuggagaaguuugacaccaaauucaaauugguguuagggg
agcuggggccuuucaaaagagagcuuuguagaggcauucuuuuugacuac
uuuucucuagcgugccauuuuaguuuuugacggcagauucgaaugaacuu
aaguuuaugaugaagguauggcuguugagauuauuuggucgggauuguag
uuugaagaugugcucuuuugagcagucucaacuuugcucguucccguuau
gggaaaaauuuuggaaggucuugguaggaacggguggaucuuauaauuuu
ugauuuau
...........<<<<.<<<<<<<<.....>>>.>>>>><<<<<<<<<.<<
<<<........<<<<<.<<<..<<<<.<.<<<.<<<<<.......>>>>>
.>>>.......>>>>>.>>>>>>>>.....................>>>>
>>>>>>>>>><<<.<<<<.<<..<<<<<.<<<<<<<..<<<<<<<<<.<<
<..<<<<<<<..>>>>>>>...>>>>>.>>>>>>>..>>>>>>>((....
...<<<<<....))>>>>>...<<<<<<<<.<....>>>>>>>>>.>>>>
><<<<<<<<<<<<<<<<<..<<<<...<<.<<<<...<<<<<..<<<<<<
..<<<<.......<<<<...<<<<<<<.<<<<<<...<<<<.<<<<<<..
..>>>>>>..>>>>......>>>>>>>>>>>>>..>>>>.>>>>..>>>>
>>.>>>>>..<<<<<....>>>>>.>>>>.>>...>>>>.<<<<<<...>
>>>>>...>>>>>>>>>>>>>>>>>.>>>>>>..>>>.>>>>........
........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6n7r A unified mechanism for intron and exon definition and back-splicing.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		Y5 Q7 R12 P13 N15 K16 N18 H43 N44 K45 L46 E64 S66 I67 S68 R69 S70 K72 M73 F78 Q102 G103 R104 R112 S115 L116 L135 I137 K138 V140 K142 K145
Binding residue
(residue number reindexed from 1)		Y5 Q7 R12 P13 N15 K16 N18 H43 N44 K45 L46 E56 S58 I59 S60 R61 S62 K64 M65 F70 Q94 G95 R96 R104 S107 L108 L120 I122 K123 V125 K127 K130
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0030619 U1 snRNA binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0071004 U2-type prespliceosome

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6n7r, PDBe:6n7r, PDBj:6n7r
PDBsum6n7r
PubMed31485080
UniProtP32605|RU1A_YEAST U1 small nuclear ribonucleoprotein A (Gene Name=MUD1)

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