Structure of PDB 6n7p Chain C Binding Site BS01

Receptor Information
>6n7p Chain C (length=132) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SALYFQNLPSRPANKENYTRLLLKHINPNNKYAINPSLPLPHNKLLLDDQ
MGLLEVSISRSSKMTNQAFLTFVTQEEADRFLEKYTTTALKVQGRKVRMG
KARTNSLLGLSIEMQKYNLDIKKVLKARKLKR
Ligand information
>6n7p Chain R (length=558) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auacuuaccuuaagauaucagaggagaguccuacugaucaaacaugcgcu
uccaauaguagaaggacguuaagcauuuaucauugaacuauaauuguuca
uugaagucauugaugcaaacuccuuggucacacacacauacggcgcggaa
ggcguguuugcugacguuuccauucccuuguuucaaucauugguuaaucc
cuugauuccuuuggggauuuuuggguuaaacugauuuuuggggcccuuug
uuucuucugccuggagaaguuugacaccaaauucaaauugguguuagggg
agcuggggccuuucaaaagagagcuuuguagaggcauucuuuuugacuac
uuuucucuagcgugccauuuuaguuuuugacggcagauucgaaugaacuu
aaguuuaugaugaagguauggcuguugagauuauuuggucgggauuguag
uuugaagaugugcucuuuugagcagucucaacuuugcucguucccguuau
gggaaaaauuuuggaaggucuugguaggaacggguggaucuuauaauuuu
ugauuuau
...........<<<<.<<<<<<<<<...>>>>.>>>>><<<<<<<<<.<<
<<<........<<<<<.<<<..<<<<.<.<<<.<<<<.........>>>>
.>>>.......>>>>>.>>>>>>>>.....................>>>>
>>>>>>>>>><<<.<<<<.<<..<<<<<.<<<<<<<..<<<<<<<<<.<<
<..<<<<<<<..>>>>>>>...>>>>>.>>>>>>>..>>>>>>>((....
...<<<<<....))>>>>>...<<<<<<<<.......>>>>>>>>.>>>>
><<<<<<<<<<<<<<<<<..<<<<...<<.<<<<...<<<<<..<<<<<<
..<<<<.......<<<<...<<<<<<<.<<<<<<...<<<<.<<<<<<..
..>>>>>>..>>>>......>>>>>>>>>>>>>..>>>>.>>>>..>>>>
>>.>>>>>..<<<<<....>>>>>.>>>>.>>...>>>>.<<<<<<...>
>>>>>...>>>>>>>>>>>>>>>>>.>>>>>>..>>>.>>>>........
........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6n7p A unified mechanism for intron and exon definition and back-splicing.
Resolution3.6 Å
Binding residue
(original residue number in PDB)		Y5 Q7 R12 N15 K16 H43 E64 S66 I67 R69 S70 K72 M73 N75 F78 Q102 G103 R104 K105 A111 R112 N114 L116 N134 L135 I137 K138 K139
Binding residue
(residue number reindexed from 1)		Y4 Q6 R11 N14 K15 H42 E55 S57 I58 R60 S61 K63 M64 N66 F69 Q93 G94 R95 K96 A102 R103 N105 L107 N118 L119 I121 K122 K123
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0030619 U1 snRNA binding
Biological Process
GO:0000395 mRNA 5'-splice site recognition
GO:0000398 mRNA splicing, via spliceosome
GO:0006397 mRNA processing
GO:0008380 RNA splicing
Cellular Component
GO:0000243 commitment complex
GO:0005634 nucleus
GO:0005681 spliceosomal complex
GO:0005685 U1 snRNP
GO:0071004 U2-type prespliceosome

View graph for
Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6n7p, PDBe:6n7p, PDBj:6n7p
PDBsum6n7p
PubMed31485080
UniProtP32605|RU1A_YEAST U1 small nuclear ribonucleoprotein A (Gene Name=MUD1)

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