Structure of PDB 6mzi Chain C Binding Site BS01

Receptor Information
>6mzi Chain C (length=233) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RVLQLKLGNSAIVTQEAANYCCAYGEWPNYLPDHEAVAIDKPTQPETATD
RFYTLKSVKWETGSTGWWWKLPDALNNIGMFGQNVQHHYLYRSGFLIHVQ
CNATKFHQGALLVVAIPEHQRGAHNTNTSPGFDDIMKGEEGGTFNHPYVL
DDGTSLACATIFPHQWINLRTNNSATIVLPWMNAAPMDFPLRHNQWTLAI
IPVVPLGTRTTSSMVPITVSIAPMCCEFNGLRH
Ligand information
>6mzi Chain D (length=28) Species: 42789 (enterovirus D68) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFYKDSYAASASKQDFSQDPSKFTEPVV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6mzi Molecular basis for the acid-initiated uncoating of human enterovirus D68.
Resolution3.46 Å
Binding residue
(original residue number in PDB)		N30 Y31 C32 C33 Y35
Binding residue
(residue number reindexed from 1)		N19 Y20 C21 C22 Y24
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6mzi, PDBe:6mzi, PDBj:6mzi
PDBsum6mzi
PubMed30530701
UniProtA0A097BW12

[Back to BioLiP]