Structure of PDB 6myp Chain C Binding Site BS01

Receptor Information
>6myp Chain C (length=139) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ATTAKEEMARFWEKNTKSSRPLSPHISIYKWSLPMAMSITHRGTGVALSL
GVSLFSLAALLLPEQFPHYVAVVKSLSLSPALIYSAKFALVFPLSYHTWN
GIRHLVWDMGKGFKLSQVEQSGVVVLILTLLSSAAIAAM
Ligand information
Ligand IDTTF
InChIInChI=1S/C8H5F3O2S/c9-8(10,11)7(13)4-5(12)6-2-1-3-14-6/h1-3H,4H2
InChIKeyTXBBUSUXYMIVOS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1cc(sc1)C(=O)CC(=O)C(F)(F)F
ACDLabs 10.04O=C(c1sccc1)CC(=O)C(F)(F)F
CACTVS 3.341FC(F)(F)C(=O)CC(=O)c1sccc1
FormulaC8 H5 F3 O2 S
Name4,4,4-TRIFLUORO-1-THIEN-2-YLBUTANE-1,3-DIONE;
2-THENOYLTRIFLUOROACETONE
ChEMBLCHEMBL1236433
DrugBankDB04795
ZINCZINC000100004957
PDB chain6myp Chain C Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB6myp Crystallographic investigation of the ubiquinone binding site of respiratory Complex II and its inhibitors.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		S39 I40 R43
Binding residue
(residue number reindexed from 1)		S38 I39 R42
Annotation score1
Enzymatic activity
Enzyme Commision number 1.3.5.1: succinate dehydrogenase.
Gene Ontology
Molecular Function
GO:0009055 electron transfer activity
GO:0046872 metal ion binding
Biological Process
GO:0006099 tricarboxylic acid cycle
Cellular Component
GO:0005739 mitochondrion
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6myp, PDBe:6myp, PDBj:6myp
PDBsum6myp
PubMed34089891
UniProtD0VWW3

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