Structure of PDB 6mwn Chain C Binding Site BS01
Receptor Information
>6mwn Chain C (length=225) Species:
9606
(Homo sapiens) [
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EVQLVESGGGLVQPGGSLRLSCAASGFSLSSSSMHWVRQAPGKGLEWVAS
ISPYSGSTSYADSVKGRFTISADTSKNTAYLQMNSLRAEDTAVYYCARTK
YHYKNYYWWALDYWGQGTLVTVSSASTKGPSVFPLAPSSKSTSGGTAALG
CLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSL
GTQTYICNVNHKPSNTKVDKKVEPK
Ligand information
>6mwn Chain A (length=92) [
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ggcaaacaucauuuggccuuaaaugggauucugugagaggggaucccucc
auugacagcuggacuguucuuuggggccuuaugugguguuug
..<<<<<<<<<<..<<<<......<<<<<<<<.......>>>>>>>>.<<
<..<<<<.......>>.>>..>>>>>>>....>>>>>>>>>>
Receptor-Ligand Complex Structure
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PDB
6mwn
A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites.
Resolution
2.838 Å
Binding residue
(original residue number in PDB)
E4 T205
Binding residue
(residue number reindexed from 1)
E1 T202
Binding affinity
PDBbind-CN
: Kd=44nM
External links
PDB
RCSB:6mwn
,
PDBe:6mwn
,
PDBj:6mwn
PDBsum
6mwn
PubMed
31399592
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