Structure of PDB 6muu Chain C Binding Site BS01

Receptor Information
>6muu Chain C (length=276) Species: 342948 (Thermococcus onnurineus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RFYGKIVIKGKIKAVTGLHIGSQIDNPVIKDPHTGLPYIPGSSLKGRLRS
LFEILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIH
VCPDYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEA
ITEAKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIK
NLLTAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVS
IDAREKSVSDILSGFDSLFSEVEGKL
Ligand information
>6muu Chain G (length=25) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guggaaaggcgggcagaggcgguuu
.........................
Receptor-Ligand Complex Structure
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PDB6muu Type III-A CRISPR-Cas Csm Complexes: Assembly, Periodic RNA Cleavage, DNase Activity Regulation, and Autoimmunity.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		I23 G24 S53 S54 K56 G57 R58 R60 S61 I105 G129 S131 N136 S139 E168 V169 I171 R173 S176 A178 R181 Y224 G226 G227 R231
Binding residue
(residue number reindexed from 1)		I20 G21 S42 S43 K45 G46 R47 R49 S50 I94 G118 S120 N125 S128 E157 V158 I160 R162 S165 A167 R170 Y213 G215 G216 R220
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6muu, PDBe:6muu, PDBj:6muu
PDBsum6muu
PubMed30503773
UniProtB6YWC0

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