Structure of PDB 6mcp Chain C Binding Site BS01

Receptor Information
>6mcp Chain C (length=507) Species: 272624 (Legionella pneumophila subsp. pneumophila str. Philadelphia 1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KNTMPLVIAYNNAPEDDKIQKLFYLQKINYLLNKTQLNDDLFDWINDAEE
GGWLNELAKFSINPNASFFLKGMQFAKAITEEIKNKPEINSSEVNIYHLM
QERDQLLKEVEFEKCATRYAEINFLLNELALNDKKTKEIVERQTEILRLV
APKIKAIKGESIDNLPVIPNFNFKFTMSGWEAPFVFRVEDRHELGKEQEL
HSYGVSKYFIEDYSVFMMRFKAEDGSTVYKPVILSQFANQNNLEEIAKQL
KDGSPKNIAPRIGYYFVQLTDFCLKLIETHNYHPDIKLNNFLVHNNRVLV
SDRKTFTTNDNPLASEILTSPLFAPDEFLKCLLFNKEGDPVGYNRNALWK
RMNMPQFMAYQLGMALKQFLILTQLDELPDDFRNPDHSAVSHFKTPSRQI
INLSLLVQELTRLDPDKRMTIKQFQTLLNFKNLPPDAFYQKVEEVFPSSQ
LGIAEDIEALNKVLNSDLKGEALLKQANPVFTKLSKYDPKETRLTRLAEK
LAIRCFN
Ligand information
Ligand IDMN
InChIInChI=1S/Mn/q+2
InChIKeyWAEMQWOKJMHJLA-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mn+2]
CACTVS 3.341[Mn++]
FormulaMn
NameMANGANESE (II) ION
ChEMBL
DrugBankDB06757
ZINC
PDB chain6mcp Chain C Residue 601 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6mcp TheLegionellakinase LegK7 exploits the Hippo pathway scaffold protein MOB1A for allostery and substrate phosphorylation.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		N312 D324
Binding residue
(residue number reindexed from 1)		N290 D302
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.1: non-specific serine/threonine protein kinase.
External links