Structure of PDB 6lbi Chain C Binding Site BS01

Receptor Information
>6lbi Chain C (length=84) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AWGNLSYADLITKAIESSAEKRLTLSQIYEWMVKSVPYFKDKGDSNSSAG
WKNSIRHNLSLHSKFIRVQNEGTGKSSWWMLNPE
Ligand information
Receptor-Ligand Complex Structure
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PDB6lbi Mechanism of forkhead transcription factors binding to a novel palindromic DNA site.
Resolution3.067 Å
Binding residue
(original residue number in PDB)		L183 R214 H215 S218 R225 S235 W237
Binding residue
(residue number reindexed from 1)		L25 R56 H57 S60 R67 S77 W79
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:6lbi, PDBe:6lbi, PDBj:6lbi
PDBsum6lbi
PubMed33577686
UniProtQ12778|FOXO1_HUMAN Forkhead box protein O1 (Gene Name=FOXO1)

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