Structure of PDB 6las Chain C Binding Site BS01

Receptor Information
>6las Chain C (length=91) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RPNHTIYINNLNEKIKKDELKKSLHAIFSRFGQILDILVKRSLKMRGQAF
VIFKEVSSATNALRSMQGFPFYDKPMRIQYAKTDSDIIAKM
Ligand information
>6las Chain B (length=55) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcauugugccucgcauugcacuccgcggggcgauaaguccugaaaaggg
auguc
<<<<<<.<<<<<<<<..........>>>>>>>>......<<<....>>>>
>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6las SAM-VI riboswitch structure and signature for ligand discrimination.
Resolution2.708 Å
Binding residue
(original residue number in PDB)		Y13 N15 N16 E19 K22 K23 D24 R47 S48 L49 K50 M51 R52 Q54 F56 K80 Q85 Y86 K88 D90 S91 D92
Binding residue
(residue number reindexed from 1)		Y7 N9 N10 E13 K16 K17 D18 R41 S42 L43 K44 M45 R46 Q48 F50 K74 Q79 Y80 K82 D84 S85 D86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:6las, PDBe:6las, PDBj:6las
PDBsum6las
PubMed31844059
UniProtP09012|SNRPA_HUMAN U1 small nuclear ribonucleoprotein A (Gene Name=SNRPA)

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