Structure of PDB 6ku0 Chain C Binding Site BS01
Receptor Information
>6ku0 Chain C (length=359) Species:
10090
(Mus musculus) [
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FQGMLEYKREDEQKLVKNLILELKPRGVAVNLIPGLPAYILFMCVRHADY
LNDDQKVRSLLTSTINSIKKVLKKRGDDFETVSFWLSNTCRFLHCLKQYS
GEEGFMKHNTSRQNEHCLTNFDLAEYRQVLSDLAIQIYQQLVRVLENILQ
PMIVSGMLEHETYTLDSILRQLNSFHSVMCQHGMDPELIKQVVKQMFYIV
GAITLNNLLLRKDMCSWSKGMQIRYNVSQLEEWLRDKNLMNSGAKETLEP
LIQAAQLLQVKKKTDDDAEAICSMCNALTTAQIVKVLNLYTPVNEFEERV
SVSFIRTIQMRLRDRKDSPQLLMDAKHIFPVTFPFNPSSLALETIQIPAS
LGLGFIARV
Ligand information
>6ku0 Chain D (length=23) Species:
9606
(Homo sapiens) [
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QPTRRQIRLSSPERQRLSSLNLT
Receptor-Ligand Complex Structure
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PDB
6ku0
F-actin disassembly factor MICAL1 binding to Myosin Va mediates cargo unloading during cytokinesis.
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
R1528 I1535 K1539 K1540 K1543 S1570 G1571 L1588 T1589 N1590 F1591 D1592 E1595 Y1596 V1599 L1603 Q1606
Binding residue
(residue number reindexed from 1)
R58 I65 K69 K70 K73 S100 G101 L118 T119 N120 F121 D122 E125 Y126 V129 L133 Q136
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6ku0
,
PDBe:6ku0
,
PDBj:6ku0
PDBsum
6ku0
PubMed
33158857
UniProt
Q99104
|MYO5A_MOUSE Unconventional myosin-Va (Gene Name=Myo5a)
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