Structure of PDB 6kdn Chain C Binding Site BS01 |
| >6kdn Chain C (length=553) Species: 11676 (Human immunodeficiency virus 1)
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PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKI
GPENPYNTPVFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGL
KQKKSVTVLDVGDAFYSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLP
MGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRT
KIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKD
SWTVNDIQKLVGKLNWASQIYAGIKVRQLSKLLRGTKALTEVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQGQWTYQIYQEPFKNLK
TGKYARMKGAHTNDVKQLTEAVQKIATESIVIWGKTPKFKLPIQKETWEA
WWTEYWQATWIPEWEFVNTPPLVKLWYQLEKEPIIGAETFYVDGAANRET
KLGKAGYVTDRGRQKVVPLTDTTNQKTELQAIHLALQDSGLEVNIVTDSQ
YALGIIQAQPDKSESELVSQIIEQLIKKEKVYLAWVPAHKGIGGNEQVDK
LVS |
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| PDB | 6kdn Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. |
| Resolution | 2.303 Å |
Binding residue
(original residue number in PDB) | W24 F61 L74 D76 R78 E89 Q91 I94 G152 P157 Y183 M184 D185 M230 G231 N255 Q258 K259 G262 K263 W266 S280 R284 K353 G359 H361 K374 R448 T473 Q475 K476 Y501 |
Binding residue
(residue number reindexed from 1) | W24 F61 L74 D76 R78 E89 Q91 I94 G152 P157 Y183 M184 D185 M230 G231 N255 Q258 K259 G262 K263 W266 S280 R284 K353 G359 H361 K374 R448 T473 Q475 K476 Y501 |
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