Structure of PDB 6kc4 Chain C Binding Site BS01
Receptor Information
>6kc4 Chain C (length=100) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
KPLAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQR
RHFIIQYVDNMYRFEGTGFSNIPQLIDHHYTTKQVITKKSGVVLLNPIPK
Ligand information
>6kc4 Chain B (length=6) Species:
32630
(synthetic construct) [
Search peptide sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
DEYENV
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
6kc4
High-resolution structural analysis shows how different crystallographic environments can induce alternative modes of binding of a phosphotyrosine peptide to the SH2 domain of Fer tyrosine kinase.
Resolution
1.37 Å
Binding residue
(original residue number in PDB)
Y509 N512
Binding residue
(residue number reindexed from 1)
Y57 N60
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:6kc4
,
PDBe:6kc4
,
PDBj:6kc4
PDBsum
6kc4
PubMed
31441171
UniProt
P16591
|FER_HUMAN Tyrosine-protein kinase Fer (Gene Name=FER)
[
Back to BioLiP
]
