Structure of PDB 6jmt Chain C Binding Site BS01

Receptor Information
>6jmt Chain C (length=339) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SSDVCADCNGPDPSWASVNRGTFICDECCSVHRSLGRHISQVRHLKHTAW
PPTLLQMVETLYNNGANSIWEHSLLDPASRKANPQDKVHPNKAEFIRAKY
QMLAFVHRLPCRESVTAKDLSKQLHSSVRTGNLETCLRLLSLGAQANFFH
PEKGSTPLHVASKAGQILQAELLAVYGADPGTQDSSGKTPVDYARQGGHH
ELAERLIEIQYELTDRLAFYLCGRKPDHKSGQHFLIPQRADAALDLSELA
KAAKKKLQSLSNHLFEELAMDVYDEVDRRETDAVWLATQNHSTLVPFLPV
NPEYSSTRNQGRQKLARFNAHEFATLVIDILSDAKRRQQ
Ligand information
Receptor-Ligand Complex Structure
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PDB6jmt GIT/PIX Condensates Are Modular and Ideal for Distinct Compartmentalized Cell Signaling.
Resolution2.8 Å
Binding residue
(original residue number in PDB)
A266 K267 K269 L270 L273 L277 L281 S324 T326 G330 F337 L345 D348
Binding residue
(residue number reindexed from 1)
A253 K254 K256 L257 L260 L264 L268 S305 T307 G311 F318 L326 D329
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005096 GTPase activator activity
Biological Process
GO:0007420 brain development
GO:0032012 regulation of ARF protein signal transduction

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Molecular Function

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Biological Process
External links
PDB RCSB:6jmt, PDBe:6jmt, PDBj:6jmt
PDBsum6jmt
PubMed32780989
UniProtQ9JLQ2|GIT2_MOUSE ARF GTPase-activating protein GIT2 (Gene Name=Git2)

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