Structure of PDB 6iqw Chain C Binding Site BS01

Receptor Information
>6iqw Chain C (length=274) Species: 523850 (Thermococcus onnurineus NA1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RFYGKIVIKGKIKAVTGLHIGSNPVIKDPHTGLPYIPGSSLKGRLRSLFE
ILVNSRLGEWREKYPSLANYSPGSCRPDNQENCGKFFNRKINRGWIHVCP
DYETALACPVCRLFGASGKESNFPSRIIVRDAFLTKEWEEKWRAGEAITE
AKIEVGIDRVTSQANPRTNERVVAGAEFEFEIIYNVENTTHWRDDIKNLL
TAMALLEDSYLGGSGSRGYGKVKFIFDSFEFRPLDYYRTGKDEDIVSIDA
REKSVSDILSGFDSLFSEVEGKLE
Ligand information
>6iqw Chain I (length=24) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
guggaaaguggcccgaaacccuuc
........................
Receptor-Ligand Complex Structure
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PDB6iqw Cryo-EM structure of Type III-A CRISPR effector complex.
Resolution3.35 Å
Binding residue
(original residue number in PDB)		G24 S25 S53 S54 K56 G57 R58 S61 I110 V112 F128 G129 A130 S131 N136 F137 P138 S139 I167 E168 V169 I171 A178 G227 S228 R231
Binding residue
(residue number reindexed from 1)		G21 S22 S39 S40 K42 G43 R44 S47 I96 V98 F114 G115 A116 S117 N122 F123 P124 S125 I153 E154 V155 I157 A164 G213 S214 R217
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004519 endonuclease activity
Biological Process
GO:0051607 defense response to virus

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Molecular Function
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Biological Process
External links
PDB RCSB:6iqw, PDBe:6iqw, PDBj:6iqw
PDBsum6iqw
PubMed30459428
UniProtB6YWC0

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