Structure of PDB 6i7a Chain C Binding Site BS01
Receptor Information
>6i7a Chain C (length=139) Species:
9606
(Homo sapiens) [
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KVVKFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLD
EESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQ
GKDWGFKKFIRRNFLLDEANGLLPDDKLTLFCEVSVVQD
Ligand information
>6i7a Chain D (length=7) Species:
9606
(Homo sapiens) [
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KADTTTP
Receptor-Ligand Complex Structure
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PDB
6i7a
Structural Insights into BET Client Recognition of Endometrial and Prostate Cancer-Associated SPOP Mutants.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
L76 Y87 Y123 K129 D130 W131 G132 F133 K134
Binding residue
(residue number reindexed from 1)
L49 Y60 Y96 K102 D103 W104 G105 F106 K107
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6i7a
,
PDBe:6i7a
,
PDBj:6i7a
PDBsum
6i7a
PubMed
31026449
UniProt
O43791
|SPOP_HUMAN Speckle-type POZ protein (Gene Name=SPOP)
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