Structure of PDB 6i3p Chain C Binding Site BS01

Receptor Information
>6i3p Chain C (length=630) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TNMSIKEQRESLPVFQFRDQIIQAVKDNQILIVVGETGSGKTTQVTQYLA
EAGFTKYGMIGCTQPRRVAAVSVAKRVAEEVGCQLGQEVGYTIRFEDVTS
PATKIKYMTDGMLQREILMDPDLKRYSVIMLDEAHERTIATDVLFALLKK
TVKRRPDLKVIVTSATLDAEKFSEYFNSCPIFTIPGRTFPVEILYSREPE
PDYLEAALTTVMQIHLTEPPGDILVFLTGQEEIDTACEILYERMKALGPS
VPELIILPIYSALPSEMQSRIFEPAPPGSRKVVIATNIAETSITIDYIYY
VVDPGFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTGPGKCFRLY
TEAAYQSEMLPTTIPDIQRQNLANTILLLKAMGINDLLRFDFMDPPPVNT
MLTALEELYALGALDDEGLLTRLGRKMADFPMEPSLSKVLIASVDKGCSD
EMVTIVSMLNLQQIFYRPKDKQQQADQKKAKFHDPTGDHLTLLNVYNAWK
NSGYSNAWCFENYIQARAMRRARDVRQQIVKIMERHRHPIISCGRDTDKI
RQALCAGFFRNTARKDPGYKTLTEGTPVYLHPSSALFGKQAEWVLYHELV
LTTKEYMHFTTAIEPKWLVEAAPTFFKLAP
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6i3p Structural basis for RNA translocation by DEAH-box ATPases.
Resolution2.75 Å
Binding residue
(original residue number in PDB)
R611 R612 R639 T654 G656 M657 R660 G774 Q775 Y805 S806 T831 N832 I833 S837 K853 L866 P976 R1012 Q1073 H1128 P1129 F1134 V1147 T1149 K1151 H1155
Binding residue
(residue number reindexed from 1)
R66 R67 R94 T109 G111 M112 R115 G229 Q230 Y260 S261 T286 N287 I288 S292 K308 L321 P431 R467 Q528 H581 P582 F587 V600 T602 K604 H608
Enzymatic activity
Enzyme Commision number 3.6.4.13: RNA helicase.
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0005524 ATP binding

View graph for
Molecular Function
External links
PDB RCSB:6i3p, PDBe:6i3p, PDBj:6i3p
PDBsum6i3p
PubMed30828714
UniProtG0S700

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