Structure of PDB 6huf Chain C Binding Site BS01

Receptor Information
>6huf Chain C (length=171) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
YLIKFLALGDSGVGKTSVLYQYTDGKFNSKFITTVGIDFREKTIYRNDKR
IKLQLWDTAGLERFRSLTTAFFRDAMGFLLLFDLTNEESFLNVRNWISQL
KTHAYSENPDIVLCGNKSDLEDERVVAAAEARQLAEHYGIPYFETSAANG
TNISQAIEMLLDLIMKRMERS
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain6huf Chain C Residue 201 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6huf Coping with strong translational noncrystallographic symmetry and extreme anisotropy in molecular replacement with Phaser: human Rab27a.
Resolution2.82 Å
Binding residue
(original residue number in PDB)		T23 T41 D64
Binding residue
(residue number reindexed from 1)		T16 T34 D57
Annotation score1
Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding

View graph for
Molecular Function
External links
PDB RCSB:6huf, PDBe:6huf, PDBj:6huf
PDBsum6huf
PubMed30950405
UniProtP51159|RB27A_HUMAN Ras-related protein Rab-27A (Gene Name=RAB27A)

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