Structure of PDB 6h06 Chain C Binding Site BS01

Receptor Information

>6h06 Chain C (length=219) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

PVQLVQSGAEVKKPGAPVKVSCETSGYRFSDYNVHWVRQAPGQGPEWIGR
ISPNSGGTKYAQKFQGRVTMTRDMSMNTAYMELSGLRSDDTAVYYCVRGH
CDGTTCSRAYWGQGTLVTVSSASTKGPSVFPLAPSSKGGTAALGCLVKDY
FPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYI
CNVNHKPSNTKVDKRVEPK

Ligand information

>6h06 Chain G (length=8) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

VDSPQLAT

Receptor-Ligand Complex Structure

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Structure summary

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PDB	6h06 Enhancement of therapeutic potential of a naturally occurring human antibody targeting a phosphorylated Ser422containing epitope on pathological tau.
Resolution	2.63 Å
Binding residue (original residue number in PDB)	N33 H35 H100 G103
Binding residue (residue number reindexed from 1)	N33 H35 H100 G103

External links

PDB	RCSB:6h06, PDBe:6h06, PDBj:6h06
PDBsum	6h06
PubMed	30001207

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