Structure of PDB 6gl1 Chain C Binding Site BS01
Receptor Information
>6gl1 Chain C (length=273) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGREPRFISVGYVDDTQFVRFDNDAASPRMVPRAPW
MEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHGC
ELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDAS
EAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEATL
RCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVPS
GEEQRYTCHVQHEGLPEPVTLRW
Ligand information
>6gl1 Chain Q (length=9) Species:
11676
(Human immunodeficiency virus 1) [
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RMYSPTSIL
Receptor-Ligand Complex Structure
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PDB
6gl1
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Resolution
2.623 Å
Binding residue
(original residue number in PDB)
Y7 R62 E63 T70 I73 N77 L81 Y84 W97 H99 S143 K146 E152 Q156 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 R61 E62 T69 I72 N76 L80 Y83 W96 H98 S142 K145 E151 Q155 Y158 W166 Y170
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6gl1
,
PDBe:6gl1
,
PDBj:6gl1
PDBsum
6gl1
PubMed
30087334
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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