Structure of PDB 6gh4 Chain C Binding Site BS01
Receptor Information
>6gh4 Chain C (length=274) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRW
Ligand information
>6gh4 Chain Q (length=9) Species:
1762
(Mycobacteriaceae) [
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RQPAKAPLL
Receptor-Ligand Complex Structure
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PDB
6gh4
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Resolution
2.16 Å
Binding residue
(original residue number in PDB)
Y7 R62 E63 S66 A67 I73 N77 Y84 W97 H99 F116 S143 K146 E152 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 R62 E63 S66 A67 I73 N77 Y84 W97 H99 F116 S143 K146 E152 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6gh4
,
PDBe:6gh4
,
PDBj:6gh4
PDBsum
6gh4
PubMed
30087334
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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