Structure of PDB 6gh1 Chain C Binding Site BS01

Receptor Information
>6gh1 Chain C (length=274) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGEGHTQDTELVETRPAGDGTFQKWAAVVVP
SGEEQRYTCHVQHEGLPEPVTLRW
Ligand information
>6gh1 Chain Q (length=9) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
RLPAKAPLL
Receptor-Ligand Complex Structure
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PDB6gh1 Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		Y7 R62 E63 A67 I73 N77 Y84 W97 H99 S143 K146 Y159 T163 W167 Y171
Binding residue
(residue number reindexed from 1)		Y7 R62 E63 A67 I73 N77 Y84 W97 H99 S143 K146 Y159 T163 W167 Y171
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:6gh1, PDBe:6gh1, PDBj:6gh1
PDBsum6gh1
PubMed30087334
UniProtP13747|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)

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