Structure of PDB 6ggm Chain C Binding Site BS01
Receptor Information
>6ggm Chain C (length=270) Species:
9606
(Homo sapiens) [
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GSHSLKYFHTSVSRPGRGEPRFISVGYVDDTQFVRFDNDAASPRMVPRAP
WMEQEGSEYWDRETRSARDTAQIFRVNLRTLRGYYNQSEAGSHTLQWMHG
CELGPDGRFLRGYEQFAYDGKDYLTLNEDLRSWTAVDTAAQISEQKSNDA
SEAEHQRAYLEDTCVEWLHKYLEKGKETLLHLEPPKTHVTHHPISDHEAT
LRCWALGFYPAEITLTWQQDGQDTELVETRPAGDGTFQKWAAVVVPSGEE
QRYTCHVQHEGLPEPVTLRW
Ligand information
>6ggm Chain Q (length=9) Species:
1762
(Mycobacteriaceae) [
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RFPAKAPLL
Receptor-Ligand Complex Structure
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PDB
6ggm
Pathogen-derived HLA-E bound epitopes reveal broad primary anchor pocket tolerability and conformationally malleable peptide binding.
Resolution
2.734 Å
Binding residue
(original residue number in PDB)
Y7 H9 M45 R62 E63 S66 A67 T70 N77 Y84 W97 H99 F116 S143 K146 E152 Y159 W167 Y171
Binding residue
(residue number reindexed from 1)
Y7 H9 M45 R62 E63 S66 A67 T70 N77 Y84 W97 H99 F116 S143 K146 E152 Y159 W167 Y171
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:6ggm
,
PDBe:6ggm
,
PDBj:6ggm
PDBsum
6ggm
PubMed
30087334
UniProt
P13747
|HLAE_HUMAN HLA class I histocompatibility antigen, alpha chain E (Gene Name=HLA-E)
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