Structure of PDB 6f5o Chain C Binding Site BS01

Receptor Information
>6f5o Chain C (length=730) Species: 1601067 (Influenza B virus (B/Memphis/13/2003)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MTLAKIELLKQLLRDNEAKTVLKQTTVDQYNIIRKFNTSRIEKNPSLRMK
WAMCSNFPLALTKGDMANRIPLEYKGIQLKTNAEDIGTKGQMCSIAAVTW
WNTYGPIGDTEGFERVYESFFLRKMRLDNATWGRITFGPVERVRKRVLLN
PLTKEMPPDEASNVIMEILFPKEAGIPRESTWIHRELIKEKREKLKGTMI
TPIVLAYMLERELVARRRFLPVAGATSAEFIEMLHCLQGENWRQIYHPGG
NKLTESRSQSMIVACRKIIRRSIVASNPLELAVEIANKTVIDTEPLKSCL
AAIDGGDVACDIIRAALGLKIRQRQRFGRLELKRISGRGFKNDEEILIGN
GTIQKIGIWDGEEEFHVRCGECRGILKKSKMKLEKLLINSAKKEDMRDLI
ILCMVFSQDTRMFQGVRGEINFLNRAGQLLSPMYQLQRYFLNRSNDLFDQ
WGYEESPKASELHGINESMNASDYTLKGVVVTRNVKVSITKNLSLIKRTG
EVIMGANDVSELESQAQLMITYDTPKMWEMGTTKELVQNTYQWVLKNLVT
LKAQFLLGKEDMFQWDAFEAFESIIPQKMAGQYSGFARAVLKQMRDQEVM
KTDQFIKLLPFCFSPPKLRSNGEPYQFLKLVLKGGGENFIEVRKGSPLFS
YNPQTEVLTICGRMMSLKGKIEDEERNRSMGNAVLAGFLVSGKYDPDLGD
FKTIEELEKLKPGEKANILLYQGKPVKVVK
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6f5o A Mechanism for the Activation of the Influenza Virus Transcriptase.
Resolution9.8 Å
Binding residue
(original residue number in PDB)
T38 R40 E42 R48 W51
Binding residue
(residue number reindexed from 1)
T38 R40 E42 R48 W51
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003968 RNA-dependent RNA polymerase activity
Biological Process
GO:0001172 RNA-templated transcription
GO:0006351 DNA-templated transcription
GO:0006370 7-methylguanosine mRNA capping
GO:0019083 viral transcription
GO:0039523 symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
GO:0039694 viral RNA genome replication
GO:0075526 cap snatching
Cellular Component
GO:0033650 host cell mitochondrion
GO:0042025 host cell nucleus
GO:0044423 virion component

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6f5o, PDBe:6f5o, PDBj:6f5o
PDBsum6f5o
PubMed29910112
UniProtQ5V8X3

[Back to BioLiP]