Structure of PDB 6cv1 Chain C Binding Site BS01

Receptor Information
>6cv1 Chain C (length=237) Species: 42789 (enterovirus D68) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDRVLQLKLGNSAIVTQEAANYCCAYGEWPNYLPDHEAVAIDKPTQPETA
TDRFYTLKSVKWEAGSTGWWWKLPDALNNIGMFGQNVQHHYLYRSGFLIH
VQCNATRFHQGALLVVAIPEHQRGAHNTNTSPGFDDIMKGEEGGTFNHPY
VLDDGTSLACATIFPHQWINLRTNNSATIVLPWMNAAPMDFPLRHNQWTL
AIIPVVPLGTRTMSSMVPITVSIAPMCCEFNGLRHAI
Ligand information
>6cv1 Chain D (length=29) Species: 42789 (enterovirus D68) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
NFYKDSYAASASKQDFSQDPSKFTEPVVE
Receptor-Ligand Complex Structure
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PDB6cv1 Bypassing pan-enterovirus host factor PLA2G16.
Resolution2.76 Å
Binding residue
(original residue number in PDB)		N30 Y31 C33 Y35
Binding residue
(residue number reindexed from 1)		N21 Y22 C24 Y26
Enzymatic activity
Enzyme Commision number 2.7.7.48: RNA-directed RNA polymerase.
3.4.22.28: picornain 3C.
3.4.22.29: picornain 2A.
3.6.1.15: nucleoside-triphosphate phosphatase.
Gene Ontology
Molecular Function
GO:0005198 structural molecule activity

View graph for
Molecular Function
External links
PDB RCSB:6cv1, PDBe:6cv1, PDBj:6cv1
PDBsum6cv1
PubMed31320648
UniProtA0A0X7Z9B1

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