Structure of PDB 6cg0 Chain C Binding Site BS01

Receptor Information
>6cg0 Chain C (length=616) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRQHLLSLTRRAQKHRLRELKIQVKEFADKEEGGDVKAVCLTLFLLALRA
RNEHRQADELEAIMQGRGSGLQPAVCLAIRVNTFLSCSQYHKMYRTVKAI
TGRQIFQPLHALRNAEKVLLPGYHPFEWQPPLKNVSSRTDVGIIDGLSGL
ASSVDEYPVDTIAKRFRYDSALVSALMDMEEDILEGMRSQDLDDYLNGPF
TVVVKESCDGMGDVSEKHGSGPAVPEKAVRFSFTVMRITIEHGSQNVKVF
EEPKPNSELCCKPLCLMLADESDHETLTAILSPLIAEREAMKSSELTLEM
GGIPRTFKFIFRGTGYDEKLVREVEGLEASGSVYICTLCDTTRLEASQNL
VFHSITRSHAENLQRYEVWRSNPYHESVEELRDRVKGVSAKPFIETVPSI
DALHCDIGNAAEFYKIFQLEIGEVYKHPNASKEERKRWQATLDKHLRKRM
NLKPIMRMNGNFARKLMTQETVDAVCELIPSEERHEALRELMDLYLKMKP
VWRSSCPAKECPESLCQYSFNSQRFAELLSTKFKYRYEGKITNYFHKTLA
HVPEIIERDGSIGAWASEGNQSGNKLFRRFRKMNARQSKCYEMEDVLKHH
WLYTSKYLQKFMNAHN
Ligand information
>6cg0 Chain F (length=46) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cgggtttttgttaagggctgtatcactgtgtaagacaggccagatc
Receptor-Ligand Complex Structure
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PDB6cg0 Cracking the DNA Code for V(D)J Recombination.
Resolution3.17 Å
Binding residue
(original residue number in PDB)		P392 L399 T400 A403 R407 Y485 K489 H501 K608 H609 G610 Q978
Binding residue
(residue number reindexed from 1)		P1 L8 T9 A12 R16 Y94 K98 H110 K217 H218 G219 Q587
Enzymatic activity
Enzyme Commision number 2.3.2.27: RING-type E3 ubiquitin transferase.
3.1.-.-
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0043565 sequence-specific DNA binding
GO:0046872 metal ion binding
GO:0061630 ubiquitin protein ligase activity
Biological Process
GO:0033151 V(D)J recombination

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Molecular Function
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Biological Process
External links
PDB RCSB:6cg0, PDBe:6cg0, PDBj:6cg0
PDBsum6cg0
PubMed29628308
UniProtP15919|RAG1_MOUSE V(D)J recombination-activating protein 1 (Gene Name=Rag1)

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