Structure of PDB 6c4h Chain C Binding Site BS01

Receptor Information
>6c4h Chain C (length=47) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
ARWRGVRPTVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKT
Ligand information
>6c4h Chain A (length=636) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
gaaccgacuaauguugaaaaauuagcggaugacuuguggcugggggugaa
aggccaaucaacuauuuagcacacggcgggugcuaacguccgucgaagau
gaaggaacuaggcaaaauggugauaccagcuggcugcaacuguuuauuaa
aaacacagcacugugcaaacacgaaaguggacguauacggugugacgccu
gcccggugccggcgguaaacggccuaagguagcgaaauuccuugucgggu
aaguuccgaccugcacgaauggcguaaugauggccaggcugucuccaccc
gagacucagugaaauugaacucgcugugaagaugcaguguacccgcggca
agacggaaagaccccgugaaccuuuacuauagcuugacugucuggugggu
aguuugacuggggcggucuccuccuaaagaguaacggaggaacggauaaa
agguacuccggggauaacaggcugauaccgcccaagaguucauaucgacg
gcgguguuuggcaccucgaugucggcucaucacauccuggggcugaagua
ggucccaaggguauggcuguucgccauuuaaagugguacgcgagcugggu
uuagaacgucgugagacaguucggucccuaucugcc
...<<<.<<<<<........>>>>>>>>................<<<...
..>>>....................<<<<<<......>>>>>>.......
..<<.........................<<<<<<<<<..<<<.......
..>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.
<<<..<<<<<<.>>>>..>>>>>........<...........<<<<<<.
....>>>>>>.....>....>>>>>..>>.>>>>>>>.....>>......
.....................<<<<<........>>>>>.......<<<.
<<<.<<......<<<<.<<<<<<..<<<<<.<<<.<<<.>>>.>>>..>>
>>>..<<<<.....>>>><<<<<<...........>>>>>>.........
>>>>..>>>>>>.......<<<<...<<<<<<...<<.......>>...>
>>>>>....>>>.>.......<<<<<.<<<<<<..<<<<<<<<<......
>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>..>...>>>.>>.
...<<<<<<<....>>>.>>>>....>>..>>>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6c4h Conformation of methylated GGQ in the Peptidyl Transferase Center during Translation Termination.
Resolution3.1 Å
Binding residue
(original residue number in PDB)		R212 W213 R217 P218 T219 V220 R221 G222 T223 A224 M225 N226 P227 V228 D229 H230 H232 G234 G235 E236 G237 R238 N239 F240 G241 K242 H243 P244 T246 P247 W248 Q251 T252 K253 G254 K255 K256 T257
Binding residue
(residue number reindexed from 1)		R2 W3 R7 P8 T9 V10 R11 G12 T13 A14 M15 N16 P17 V18 D19 H20 H22 G24 G25 E26 G27 R28 N29 F30 G31 K32 H33 P34 T36 P37 W38 Q41 T42 K43 G44 K45 K46 T47
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0016740 transferase activity
GO:0019843 rRNA binding
Biological Process
GO:0000027 ribosomal large subunit assembly
GO:0002181 cytoplasmic translation
GO:0006412 translation
GO:0032297 negative regulation of DNA-templated DNA replication initiation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015934 large ribosomal subunit
GO:0022625 cytosolic large ribosomal subunit
GO:1990082 DnaA-L2 complex
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:6c4h, PDBe:6c4h, PDBj:6c4h
PDBsum6c4h
PubMed29403017
UniProtP60422|RL2_ECOLI Large ribosomal subunit protein uL2 (Gene Name=rplB)

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